CSC news roundup: 2009-10-06

• Tumour-initiating cells: challenges and opportunities for anticancer drug discovery by Bin-Bing S Zhou and 5 co-authors, including Peter B Dirks, Nat Rev Drug Discov 2009(Oct); 8(10): 806-23 (Review) [PubMed Citation].


• The hypoxic microenvironment maintains glioblastoma stem cells and promotes reprogramming towards a cancer stem cell phenotype by John M Heddleston and 4 co-authors, including Jeremy N Rich, Cell Cycle 2009(Oct 3); 8(20) [Epub ahead of print][PubMed Citation].


• Identification of a myeloid committed progenitor as the cancer initiating cell in acute promyelocytic leukemia by Florence C Guibal and 11 co-authors, including Daniel G Tenen, Blood 2009(Oct 1) [Epub ahead of print][PubMed Citation].


• Targeting leukaemia at the roots by Alison Ross, Science Update blog, Cancer Research UK, September 28, 2009.


• "Tax-ing" the cancer stem cell by Gerold Feuer, Blood 2009(Sep 24); 114(13): 2568-9 [PubMed Citation].


• Cancer stem cell research gains traction, tackles new targets by Katherine Harmon, Scientific American, September 23, 2009 [FriendFeed entry].


• A progenitor cell origin of myeloid malignancies by Hiroshi Haeno, Ross L Levine, D Gary Gilliland and Franziska Michor, Proc Natl Acad Sci USA 2009(Sep 29); 106(39): 16616-21 [Epub 2009(Sep 21)][PubMed Citation].


• Vitro's Cancer Stem Cell Therapy Complements New Hedge Hog Drugs, News Release, September 10, 2009 [Vitro Biopharma].


• Cancer stem cells in breast cancer and metastasis by Jessica C Lawson, Gregory L Blatch and Adrienne L Edkins, Breast Cancer Res Treat 2009(Sep 4) [Epub ahead of print] (Review). [PubMed Citation].


• Cancer stem cell genomics: the quest for early markers of malignant progression by Oswaldo K Okamoto, Expert Rev Mol Diagn 2009(Sep); 9(6): 545-54 (Review). [PubMed Citation].